Research Article
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Article title
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Abstract
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Key words
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Introduction
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Material and methods
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Fungal material
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Morphological characterization
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DNA isolation, amplification and phylogenetic study
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Cultivation and extraction of T. bulbillosa
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Data processing with MZmine
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GNPS feature-based molecular networking
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Metabolite annotation using SIRIUS
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Isolation of compounds
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Spectroscopic and spectrometric analysis of the isolated compounds
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Mosher’s derivatization
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MALDI-mass spectrometry imaging
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MSI sample preparation
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Image acquisition
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Bioactivity assays
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Assay with Caenorhabditis elegans
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Cell culture and cell survival rate
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NCI-60 human tumor cell lines screen
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List of abbreviations
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Results and discussion
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Phylogenetic analysis of the fungal endophyte
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Taxonomy
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Isolation and structure elucidation of bulbillosin A – E
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Mass spectrometry imaging
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Human tumor cell line screen of bulbillosin A (1)
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Conclusions
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Acknowledgements
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Additional information
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Conflict of interest
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Ethical statement
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Adherence to national and international regulations
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Funding
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Author contributions
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Author ORCIDs
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Data availability
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References
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Supplementary material
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